Quite a bit, actually. Yes, the original Ditko issues have a certain innocence about them, but at bottom existed a hardened cynicism about viewing life from the outside. It's been pointed out that comicdom's obsession with dual identities stems from the fact that a great many of the creators were Jewish. Certainly very few heros conformed to the "blonde, blue-eyed, all-American" ideal. Superman, Batman, and Spider-Man were all dark haired outsiders who were feared and despised for what they were, rather than what they did (which was always good). It wouldn't be a stretch to say that Lex Luthor or J. Jonah Jamison represented a typical anti-semite in their unreasoning hatred of Superman or Spider-Man. In that sense, the alter-ego (Clark Kent, Peter Parker) represents the Jewish American experience of assimilation. How many of these writers and artists overheard anti-semitic remarks by people who didn't know that they were in the presence of Jews? After all, Stanley Leiber changed his name to Stan Lee. It's not difficult to imagine that Peter listening to one of Jonah's anti-Spider-Man diatribes (unaware that he was in the presence of Spider-Man himself) refers to this experience.
Interesting take. I think Spiderman 1 did a pretty good job of translating that into a movie without slowing things down too much. That is, what's implicit in the comic is, for the most part, implicit in the movie as well. Which is kind of a miracle for Hollywood, of any era. In fact, I think it's a better "comic book movie" (pracitically a genre to itself) than the first Superman film. Just my opinion.