Oh my goodness, how much do you want to talk about this? I've lived in Saskatoon, Des Moines, and a Minneapolis suburb. And travel across parts of the big empty nearly every year for most of my life. The plains are a beautiful and unique place (although if you're talking about the Canadian part, 'prairies' is the preferred term). And it's not all the same at all, Montana east of the Rockies is a very different place than Iowa. Aberdeen SK, where my brother lives:
The Empire Builder on the trestle just outside Cut Bank MT, you can just see the Rocky Mountain front in the background. My wife has relatives here, and it's on the way to SK, so I've been there many times. Also took the Builder through this country coming and going last year. I've thought about retiring somewhere just east of the front - it's the best of both worlds to me. Cut Bank, Shelby, Havre on the High Line, all familiar territory.